Licorice Root
Glycyrrhiza glabra
Licorice root is a classic demulcent and harmonizing herb used for irritated mucosa, cough, and digestive soothing, but it requires caution because of blood-pressure effects.
Primary Use
Upper digestive soothing
Common Forms
DGL, Whole-root
Typical Dose
380-760 mg
Time to Effect
2-4 weeks
Overview
Licorice root has been used in European, Middle Eastern, Ayurvedic, and Chinese herbal traditions for thousands of years. It has served as a soothing remedy for sore throat, cough, stomach irritation, and general weakness, and in traditional formulas it is often used to harmonize or moderate stronger herbs.
Modern supplement use includes whole licorice root, deglycyrrhizinated licorice (DGL), teas, and extracts. DGL is especially popular for upper digestive support because it reduces the blood-pressure concerns linked to glycyrrhizin. Whole licorice remains useful, but it is not an herb to take casually in high doses for long periods.
How It Works
Licorice contains glycyrrhizin and flavonoids that influence inflammation, mucosal defense, and stress-related hormonal pathways. In the digestive tract, licorice may help increase protective mucus and support tissue resilience.
Whole licorice can also inhibit the breakdown of cortisol, which may contribute to some of its traditional energizing and anti-inflammatory effects. That same mechanism partly explains why it can raise blood pressure, lower potassium, and create serious side effects in susceptible people.
What It's Used For
Upper digestive soothing
DGL is commonly used for reflux-like discomfort, gastritis, and irritated stomach or esophageal tissue. Clinical evidence is moderate, with stronger support for symptom relief than for curing underlying disease.
Sore throat and cough support
Licorice is a traditional demulcent that can soothe inflamed throat tissue and support cough formulas. This use is well established traditionally and supported by its mucosal effects.
Anti-inflammatory support
Licorice compounds show anti-inflammatory and antioxidant activity in laboratory settings. Clinical application is plausible but often limited by safety concerns with long-term whole-root use.
Formula harmonizing
In traditional systems, licorice is often used to soften harsh formulas and support tolerance. This is a traditional benefit rather than a modern trial-driven one.
Dots indicate strength of research evidence (5 = strongest)
Disclaimer: This information is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider before starting any new supplement, especially if you have a medical condition or take medications.
Last updated: April 2026